Phenolic glycolipid

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August undefined, 2024

WebA phenolic glycolipid from Mycobacterium leprae was purified and used as antigen in an enzyme-linked immunosorbent assay. Antibodies directed against the lipid were seen in serums from leprosy patients but not in serums from uninfected controls or patients infected with other mycobacteria, including Mycobacterium tuberculosis. Web8. júl 1988 · A method for the structural determination of partially methylated methyl glycosides is described. The proposed method, which is an alternative to that using alditol aceta … Partially methylated glycosides play an important role in the stereospecificity of glycolipid antigen-antibody binding reactions.

Structures of Phenolic Glycolipids from Mycobacterium Kansasii

Web17. mar 2024 · Phenolic glycolipid I (PGL-I) is an abundant antigen on the Mycobacterium leprae cell wall, commonly used for operational classification of leprosy patients. Our aim … WebQuantification of anti-phenolic glycolipid-1 (PGL-1) IgM antibodies of M. leprae was obtained by the enzyme-linked immunosorbent assay method and anti-natural octyl … docker portainer installation

Role of the cell wall phenolic glycolipid-1 in the peripheral nerve

WebPhenolic glycolipid 1 (PGL-1) is a cell wall antigen on the surface of M. leprae, which binds to complement (Hunter et al., 1982). This combination of complement and M. leprae … Webthe three following classes : phenolic glycolipids (Phe GI), acyl- trehalose-containing lipooligosaccharides and polar glyco- peptidolipids. The renewal of interest in the … Web14. jún 2024 · Abstract and Figures BACKGROUND Mycobacterium leprae, the causative agent of Hansen’s disease, causes neural damage through the specific interaction between the external phenolic glycolipid-1... docker plugin install offline

Phenolic Glycolipid - an overview ScienceDirect Topics

Specific binding of phenolic glycolipid antigens from …

Web25. jan 2008 · Phenolic glycolipids (PGLs) are polyketide-derived virulence factors produced by Mycobacterium tuberculosis, M. leprae, and other mycobacterial pathogens. We have … Web30. máj 2015 · The aim of this study was to analyze the factors associated with anti-phenolic glycolipid-I (PGL-I) seropositivity among the household contacts of leprosy … docker port all interfacesWeb6. Biosynthesis and Genetics of the Phthiocerol-Containing Lipids. Phenolic glycolipids (PGLs) are polyketide-derived virulence factors produced by many pathogenic … docker port already allocated

"Web1. máj 2004 · Phenolic glycolipid-I (PGL-I), a Mycobacterium leprae -specific antigen, has been widely used for the serodiagnosis of leprosy and has been implicated in the … " - Phenolic glycolipid

Phenolic glycolipid

WebBackground: Leprosy is a neglected tropical disease caused by Mycobacterium leprae, leading to disabilities if untreated. The ELISA based on phenolic glycolipid I (PGL-I), or its synthetic version ND-O-BSA, is almost universally positive in multibacillary leprosy and thus extensively used in endemic countries. Household contacts with a positive antibody titer … WebPhenolic Glycolipid. Phenolic glycolipids have been detected in many mycobacteria and large amounts of an apparently unique one, phenolic glycolipid-I (PGL-I), is found in the …

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Phenolic glycolipids (PGLs) are polyketide-derived virulence factors produced by many pathogenic mycobacteria, notably M. tuberculosis, Mycobacterium bovis and M. leprae. From: Microbial Glycobiology, 2010 Virulence View all Topics Add to Mendeley Download as PDF About this page Biosynthesis of the mycobacterial cell envelope components Web16. júl 2004 · Phenolic glycolipids K6 and K7 have been referred to as controlled degradation products of phenolic glycolipid KI previously. Also isolated was 5-mycolyl-β …

WebPhenolic glycolipid I (PGL-I) is a Mycobacterium leprae-specific antigen and the antibodies to the antigen may suggest an M. leprae infection. To compare the M. leprae transmission among the populations, we compared the prevalence of anti-PGL-I IgM antibodies among household contacts and controls between Korea and the Philippines. WebThe phenolic glycolipid of Mycobacterium tuberculosis differentially modulates the early host cytokine response but does not in itself confer hypervirulence. Mycobacterium …

Web17. dec 2024 · Phenolic glycolipid-I (PGL−I, Figure 1) is a cell wall component of M. leprae which modulates the host immune response by limiting the production of nitric oxides … Webbacterial phenolic glycolipids was investigated. The phenolic glycolipid from M. kattsasii (PheGi K-I), the Fig. I, Inhibiticn ELISA of PheGl B antiserum binding to coated PheGl B by …

Web27. okt 2000 · Role of the cell wall phenolic glycolipid-1 in the peripheral nerve predilection of Mycobacterium leprae. The cell wall of pathogenic mycobacteria is abundant with …

Web17. apr 2024 · Mycobacterium leprae causes leprosy, and is unique among mycobacterial diseases in producing peripheral neuropathy. This debilitating morbidity is attributed to … docker port forwarding udpWeb17. feb 2024 · The phenolics of noni fruit possess antihyperglycemic activity; however, the molecular mechanisms remain unclear. To understand the potential effects it has on type … docker portainer install raspberry piWebEffects of anti leprosy drugs on phenolic glycolipid 1 synthesis by mycobacterium leprae in macrophages Ramasesh, N.; Hastings, R.; Krahenbuhl, J. Abstracts of the Annual Meeting of the American Society for Microbiology 87: 127 1987. ISSN/ISBN: 0094-8519 Accession: 028200789. Download citation: docker port forwarding -pWeb19. sep 2024 · We defined a critical role for mycobacterial membrane phenolic glycolipid (PGL) in engineering this transition. PGL activated the STING cytosolic sensing pathway … docker port forward ipWebMeasurement of serum IgM, IgG, and IgA against phenolic glycolipid antigen-1 (PGL-1) was done by an indirect enzyme-linked immunosorbent assay. Results: Twenty-three … docker port forwarding to hostWeb17. apr 2024 · Mycobacterium leprae causes leprosy, and is unique among mycobacterial diseases in producing peripheral neuropathy. This debilitating morbidity is attributed to axon demyelination resulting from direct interactions of the M. leprae -specific phenolic glycolipid 1 (PGL-1) with myelinating glia, and their subsequent infection. docker port forwarding windowsWeb15. mar 2010 · Phenolic glycolipid–I (PGL-I) of Mycobacterium leprae is a specific antigen for leprosy, and its terminal residue (ie, 3,6-di-O-methyl glucose) has not been found in … docker port mapping not working